| Characteristic | Overall N = 7621 |
Q1 N = 1911 |
Q2 N = 1911 |
Q3 N = 1891 |
Q4 N = 1911 |
p-value2 |
|---|---|---|---|---|---|---|
| Age | 71 (62, 79) | 77 (67, 84) | 74 (65, 80) | 70 (63, 76) | 64 (55, 73) | <0.001 |
| Female sex | 279 (37%) | 85 (45%) | 89 (47%) | 58 (31%) | 47 (25%) | <0.001 |
| Smoking | 0.6 | |||||
| never | 269 (36%) | 57 (31%) | 75 (40%) | 69 (38%) | 68 (36%) | |
| current | 211 (28%) | 56 (31%) | 45 (24%) | 53 (29%) | 57 (30%) | |
| prior | 262 (35%) | 70 (38%) | 66 (35%) | 62 (34%) | 64 (34%) | |
| Hypertension | 418 (55%) | 123 (65%) | 114 (60%) | 96 (51%) | 85 (45%) | <0.001 |
| Diabetes | 85 (11%) | 27 (14%) | 27 (14%) | 19 (10%) | 12 (6.3%) | 0.040 |
| Previous ischemic event | 97 (13%) | 30 (16%) | 24 (13%) | 27 (14%) | 16 (8.4%) | 0.14 |
| SVD score | <0.001 | |||||
| 0 | 310 (41%) | 49 (26%) | 72 (38%) | 81 (43%) | 108 (57%) | |
| 1 | 195 (26%) | 47 (25%) | 53 (28%) | 42 (22%) | 53 (28%) | |
| 2 | 148 (19%) | 54 (28%) | 42 (22%) | 37 (20%) | 15 (7.9%) | |
| 3 | 73 (9.6%) | 30 (16%) | 14 (7.3%) | 19 (10%) | 10 (5.2%) | |
| 4 | 36 (4.7%) | 11 (5.8%) | 10 (5.2%) | 10 (5.3%) | 5 (2.6%) | |
| Admission NIHSS | 4.0 (2.0, 7.0) | 5.0 (2.0, 9.0) | 3.0 (2.0, 8.0) | 4.0 (2.0, 8.0) | 3.0 (2.0, 5.0) | <0.001 |
| 1 Median (Q1, Q3); n (%) | ||||||
| 2 Kruskal-Wallis rank sum test; Pearson’s Chi-squared test | ||||||